Monthly Archives: October 2014
Unlocking Enzyme Synthesis of Rare Sugars to Create Drugs with Fewer Side Effects
Posted in: Scientific Highlights,
In a paper published in Structure, a team led by the U.S. Department of Energy’s Oak Ridge National Laboratory reported the pioneering use of neutron and X-ray crystallography and high performance computing to study how the enzyme D-xylose isomerase, or XI, can cause a biochemical reaction in natural sugar to produce rare sugars. Unlike drugs made
Read MoreA team from Oak Ridge National Laboratory and the University of Tennessee studied carbon fibers made from lignin, a woody plant polymer known as, and found a mixture of perfectly spherical nanoscale crystallites distributed within a fibrous matrix. They found the lignin fiber’s unique structure could make it useful as a battery anode, potentially improving
Read MoreNeutron scattering research at the Department of Energy’s Oak Ridge National Laboratory has revealed clear structural differences in the normal and pathological forms of a protein involved in Huntington’s disease. Huntington’s disease, an incurable neurodegenerative disorder, starts as a genetic mutation that leads to an overabundance of “huntingtin” protein fragments, which form clumps in the
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